Select Page
NIH Lung Tissue Research Consortium

The Lung Tissue Research Consortium (LTRC) is a resource program of the NHLBI that provides human lung tissues to qualified investigators for use in their research. The program enrolls donor subjects who are anticipating lung surgery, collects blood and extensive phenotypic data from the prospective donors, and then processes their surgical waste tissues for research use. Most donor subjects have interstitial fibrotic lung disease or COPD.

A standardized protocol is followed to assure high quality and uniformity of the data and biospecimens, and tissue samples are processed to allow pathological study, immunohistochemistry, gene expression analyses, biomarker measurements, genetic analyses, and electron microscopy. Phenotypic data include clinical and pathological diagnoses, chest CT images, pulmonary function tests, exposure and symptom questionnaires, and exercise tests. The LTRC provides tissues and data to approved investigators free of charge, but the LTRC does not provide funding to support research.

As of January 2014, the LTRC dataset included 1,007 samples with the following alpha-1 antitrypsin genotypes:

  • MZ = 49 (4%)
  • MS = 65 (6%)
  • SS = 3 (0.3%)
  • ZZ = 2 (0.2%)
  • MM = 888 (88%)

Accreditations

Alpha-1 Events Calendar

April

May 2020

June
S
M
T
W
T
F
S
27
28
29
30
31
1
2
Events for May

1st

No Events
Events for May

2nd

No Events
3
4
5
6
7
8
9
Events for May

3rd

No Events
Events for May

4th

Events for May

5th

No Events
Events for May

6th

No Events
Events for May

7th

No Events
Events for May

8th

No Events
Events for May

9th

10
11
12
13
14
15
16
Events for May

10th

No Events
Events for May

11th

No Events
Events for May

12th

No Events
Events for May

13th

No Events
Events for May

14th

No Events
Events for May

15th

No Events
Events for May

16th

17
18
19
20
21
22
23
Events for May

17th

No Events
Events for May

18th

No Events
Events for May

19th

No Events
Events for May

20th

No Events
Events for May

21st

No Events
Events for May

22nd

No Events
Events for May

23rd

24
25
26
27
28
29
30
Events for May

24th

No Events
Events for May

25th

No Events
Events for May

26th

No Events
Events for May

27th

No Events
Events for May

28th

No Events
Events for May

29th

No Events
Events for May

30th

No Events
31
1
2
3
4
5
6
Events for May

31st

No Events