fbpx
Select Page
DNA & Tissue Bank
Petry Dishes Alpha-1 DNA

The mission of the Alpha-1 Foundation DNA and Tissue Bank at the University of Florida is to provide researchers with DNA, plasma and tissue from patients with Alpha-1 Antitrypsin Deficiency to promote discovery and new therapies relevant to people with Alpha-1.

The bank, established in 2002, has more than 2,500 members enrolled and is available for researchers to request medical information (the names of donors are not revealed) and samples for research projects. Mark Brantly, MD, is the principal investigator and supervisor of the DNA and Tissue Bank.

Most enrolled subjects have provided medical information and blood samples. In addition, pulmonary function and liver enzyme testing results are a part of the bank’s data set.

High-quality genomic DNA, plasma and limited amounts of lung and liver tissue, paired with an extensive clinical database, are available for researchers interested in Alpha-1 Antitrypsin Deficiency. The collection includes spouses and family members as controls, along with a large cohort of alpha-1 antitrypsin deficient individuals maintained with regulatory control UF IRB 201500842 (formerly 659-2002), operating under an NIH confidentiality agreement. The collection includes 2393 DNA and plasma samples, specifically 805 PI ZZ, 221 Rare/null, 87 SZ, 3 SS, 478 MZ, 109 MS, and 689 MM samples.

In addition, the collection includes formalin-fixed lung tissue from 22 people, including 13 ZZ, 5 MM, 1 MF, 2 MZ, and 1 MS, plus 19 liver samples, including 16 ZZ, 2 MZ and 1 MS. The number of fresh frozen samples available for study is limited.

Researchers wishing to obtain samples of DNA and tissue should contact David Fernandez, at dfernandez@alpha1.org or at (877) 228-7321 ext. 242.

Accreditations

Alpha-1 Events Calendar

August 2021

S
M
T
W
T
F
S
1
2
3
4
5
6
7
Events for August

1st

No Events
Events for August

2nd

No Events
Events for August

3rd

No Events
Events for August

4th

No Events
Events for August

5th

Events for August

6th

No Events
Events for August

7th

No Events
8
9
10
11
12
13
14
Events for August

8th

No Events
Events for August

9th

No Events
Events for August

10th

No Events
Events for August

11th

No Events
Events for August

12th

No Events
Events for August

13th

No Events
Events for August

14th

15
16
17
18
19
20
21
Events for August

15th

No Events
Events for August

16th

No Events
Events for August

17th

No Events
Events for August

18th

No Events
Events for August

19th

No Events
Events for August

20th

No Events
Events for August

21st

No Events
22
23
24
25
26
27
28
Events for August

22nd

No Events
Events for August

23rd

No Events
Events for August

24th

Events for August

25th

No Events
Events for August

26th

No Events
Events for August

27th

No Events
Events for August

28th

29
30
31
1
2
3
4
Events for August

29th

No Events
Events for August

30th

No Events
Events for August

31st

No Events