Last Month on Pubmed

This is a series of the latest published research on Alpha-1 Antitrypsin Deficiency. It is updated monthly, based on a search. Previous months’ listings are archived in the left sidebar of this page.

December 2018 Publications

Engineering of serine protease for improved thermostability and catalytic activity using rational design. Ashraf NM, Krishnagopal A, Hussain A, Kastner D, Sayed AMM, Mok YK, Swaminathan K, Zeeshan N. Int J Biol Macromol. 2018 Dec 24;126:229-237. doi: 10.1016/j.ijbiomac.2018.12.218. [Epub ahead of print] PMID: 30590144 [PubMed - as supplied by publisher]

Serine protease inhibitors rich Coccinia grandis (L.) Voigt leaf extract induces protective immune responses in murine visceral leishmaniasis. Pramanik A, Paik D, Pramanik PK, Chakraborti T. Biomed Pharmacother. 2018 Dec 21;111:224-235. doi: 10.1016/j.biopha.2018.12.053. [Epub ahead of print] PMID: 30584985 [PubMed - as supplied by publisher] Free Article

An unusual case of alpha-1-antitrypsin deficiency: SZ/Z. Speevak MD, DeMarco ML, Wiebe NS, Chapman KR. Clin Biochem. 2018 Dec 21. pii: S0009-9120(18)30960-3. doi: 10.1016/j.clinbiochem.2018.12.008. [Epub ahead of print] PMID: 30579752 [PubMed - as supplied by publisher]

Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology. Damalanka VC, Han Z, Karmakar P, O'Donoghue AJ, La Greca F, Kim T, Pant S, Helander J, Klefström J, Craik CS, Janetka JW. J Med Chem. 2018 Dec 20. doi: 10.1021/acs.jmedchem.8b01536. [Epub ahead of print] PMID: 30571119 [PubMed - as supplied by publisher]

The Lord of the Bacteria: The fellowship of the leader and other serine protease inhibitors. Burchacka E, Sieńczyk M. Curr Pharm Des. 2018 Dec 19. doi: 10.2174/1381612825666181219163922. [Epub ahead of print] PMID: 30569850 [PubMed - as supplied by publisher]

Mitochondrial localization of St14-encoding transmembrane serine protease is involved in neural stem/progenitor cell bioenergetics through binding to F<sub>0</sub>F<sub>1</sub>-ATP synthase complex. Fang JD, Tung HH, Lee SL. FASEB J. 2018 Dec 19:fj201801307R. doi: 10.1096/fj.201801307R. [Epub ahead of print] PMID: 30566397 [PubMed - as supplied by publisher]

Kn-Ba: a novel serine protease isolated from <i>Bitis arietans</i> snake venom with fibrinogenolytic and kinin-releasing activities. Megale ÂAA, Magnoli FC, Kuniyoshi AK, Iwai LK, Tambourgi DV, Portaro FCV, da Silva WD. J Venom Anim Toxins Incl Trop Dis. 2018 Dec 13;24:38. doi: 10.1186/s40409-018-0176-5. eCollection 2018. PMID: 30564275 [PubMed] Free PMC Article

The serine protease testisin is present on the surface of capacitated stallion spermatozoa and interacts with key zona pellucida binding proteins. Swegen A, Smith ND, Gibb Z, Curry BJ, Aitken RJ. Andrology. 2018 Dec 13. doi: 10.1111/andr 12569. [Epub ahead of print] PMID: 30549223 [PubMed - as supplied by publisher]

Alternaria-induced barrier dysfunction of nasal epithelial cells: role of serine protease and reactive oxygen species. Shin SH, Ye MK, Lee DW, Che MH. Int Forum Allergy Rhinol. 2018 Dec 12. doi: 10.1002/alr.22266. [Epub ahead of print] PMID: 30548421 [PubMed - as supplied by publisher]

Alpha 1 Antitrypsin Gene Therapy Extends the Lifespan of Lupus-Prone Mice. Elshikha AS, Yuan Y, Lu Y, Chen MJ, Abboud G, Akbar MA, Plate H, Wolney H, Hoffmann T, Tagari E, Zeumer L, Morel L, Song S. Mol Ther Methods Clin Dev. 2018 Oct 18;11:131-142. doi: 10.1016/j.omtm.2018.10.007. eCollection 2018 Dec 14. PMID: 30547047 [PubMed] Free PMC Article

Expression and characterization of Flavikunin: A Kunitz-type serine protease inhibitor identified in the venom gland cDNA library of Bungarus flaviceps. Kaur S, Devi A, Saikia B, Doley R. J Biochem Mol Toxicol. 2018 Dec 10:e22273. doi: 10.1002/jbt.22273. [Epub ahead of print] PMID: 30536558 [PubMed - as supplied by publisher]

Immunolocalization of serpins in the regenerating tail of lizard suggests a role for epidermal and neural barrier formation. Alibardi L. Zoology (Jena). 2018 Dec 131:1-9. doi: 10.1016/j.zool.2018.09.002. Epub 2018 Sep 22. PMID: 30502822 [PubMed - in process]

Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles. Amann T, Hansen AH, Kol S, Hansen HG, Arnsdorf J, Nallapareddy S, Voldborg B, Lee GM, Andersen MR, Kildegaard HF. Metab Eng. 2018 Dec 1;52:143-152. doi: 10.1016/j.ymben 2018.11.014. [Epub ahead of print] PMID: 30513349 [PubMed - as supplied by publisher]

Portuguese consensus document for the management of alpha-1-antitrypsin deficiency. Lopes AP, Mineiro MA, Costa F, Gomes J, Santos C, Antunes C, Maia D, Melo R, Canotilho M, Magalhães E, Vicente I, Valente C, Gonçalves BG, Conde B, Guimarães C, Sousa C, Amado J, Brandão ME, Sucena M, Oliveira MJ, Seixas S, Teixeira V, Telo L. Pulmonology. 2018 Dec;24 Suppl 1:1-21. doi: 10.1016/j.pulmoe 2018.09.004. PMID: 30473034 [PubMed - in process] Free Article

Heterologous expression and characterization of a novel serine protease from Daphnia magna: A possible role in susceptibility to toxic cyanobacteria. Lange J, Demir F, Huesgen PF, Baumann U, von Elert E, Pichlo C. Aquat Toxicol. 2018 Dec 205:140-147. doi: 10.1016/j.aquatox.2018.09.013. Epub 2018 Sep 26. PMID: 30384195 [PubMed - indexed for MEDLINE]

Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, Jiang H. Insect Biochem Mol Biol. 2018 Dec;103:53-69. doi: 10.1016/j.ibmb.2018.10.006. Epub 2018 Oct 24. PMID: 30367934 [PubMed - in process]

Characterization of an antigenic serine protease in the Trichinella spiralis adult. Gao H, Tang B, Bai X, Wang L, Wu X, Shi H, Wang X, Liu X, Liu M. Exp Parasitol. 2018 Dec;195:8-18. doi: 10.1016/j.exppara.2018.09.009. Epub 2018 Sep 21. PMID: 30248330 [PubMed - indexed for MEDLINE]

Engineering varied serine protease inhibitors by converting P1 site of BF9, a weakly active Kunitz-type animal toxin. Ding L, Hao J, Luo X, Chen Z. Int J Biol Macromol. 2018 Dec;120(Pt A):1190-1197. doi: 10.1016/j.ijbiomac.2018.08.178. Epub 2018 Aug 30. PMID: 30172807 [PubMed - indexed for MEDLINE]

Clinical and histologic features of adults with alpha-1 antitrypsin deficiency in a non-cirrhotic cohort. Clark VC, Marek G, Liu C, Collinsworth A, Shuster J, Kurtz T, Nolte J, Brantly M. J Hepatol. 2018 Dec;69(6):1357-1364. doi: 10.1016 j.jhep.2018.08.005. Epub 2018 Aug 21. PMID: 30138687 [PubMed - in process]

Effect of two recombinant Trichinella spiralis serine protease inhibitors on TNBS-induced experimental colitis of mice. Xu J, Wu L, Yu P, Liu M, Lu Y. Clin Exp Immunol. 2018 Dec;194(3):400-413. doi: 10.1111/cei.13199. Epub 2018 Sep 23. PMID: 30105843 [PubMed - in process]

Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm-egg binding. Shang X, Shen C, Liu J, Tang L, Zhang H, Wang Y, Wu W, Chi J, Zhuang H, Fei J, Wang Z. Cell Mol Life Sci. 2018 Dec;75(23) 4371-4384. doi: 10.1007/s00018-018-2878-9. Epub 2018 Jul 21. PMID: 30032357 [PubMed - indexed for MEDLINE] Free PMC Article

Host-Derived Serine Protease Inhibitor 6 Provides Granzyme B-Independent Protection of Intestinal Epithelial Cells in Murine Graft-versus-Host Disease. Mohammadpour H, Du W, O'Neill R, Khalili S, Qiu J, Repasky EA, McCarthy PL, Cao X. Biol Blood Marrow Transplant. 2018 Dec;24(12):2397-2408. doi: 10.1016/j.bbmt 2018.07.003. Epub 2018 Jul 10. PMID: 30006303 [PubMed - in process]

Alpha 1 Antitrypsin Deficiency. Meseeha M, Attia M. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. PMID: 28723059 [PubMed] Free Books & Documents


This list of publications was generated on PubMed using the following Keywords:plus


    • alpha 1-Antitrypsin
    • alpha one antitrypsin
    • alpha 1 antitrypsine
    • alpha1-AT deficiency
    • alpha-1-AT
    • alpha 1 antiproteinase
    • alpha 1 antiprotease
    • alpha 1 protease
    • alpha 1 proteinase
    • familial emphysema
    • genetic emphysema
    • AATD
    • A1AT
    • hA1AT
    • A1-AT
    • A1P1
    • Prolastin
    • Aralast
    • Zemaira
    • Glassia