Last Month on Pubmed

This is a series of the latest published research on Alpha-1 Antitrypsin Deficiency. It is updated monthly, based on a search. Previous months’ listings are archived in the left sidebar of this page.

May 2018 Publications

Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants. Hartz A, Schreiter L, Pagel J, Moser K, Wieg C, Grotheer A, Rupp J, Herting E, Göpel W, Härtel C. Pediatr Res. 2018 May 28. doi: 10.1038/s41390-018-0017-9. [Epub ahead of print] PMID: 29807983

SERPINA1 Hepatocyte-Specific Promoter Polymorphism Associate with Chronic Obstructive Pulmonary Disease in a Study of Kashmiri Ancestry Individuals. Bashir A, Hazari YM, Bashir S, Hilal N, Banday M, Iqbal MK, Jan TR, Farooq SS, Shah NN, Fazili KM. Lung. 2018 May 26. doi: 10.1007/s00408-018-0124-8. [Epub ahead of print] PMID: 29804144

Serine Protease Inhibitor SERPINE2 Reversibly Modulates Murine Sperm Capacitation. Li SH, Hwu YM, Lu CH, Lin MH, Yeh LY, Lee RK. Int J Mol Sci. 2018 May 19;19(5). pii: E1520. doi: 10.3390/ijms19051520. PMID: 29783741

Alpha-1-antitrypsin ameliorates inflammation and neurodegeneration in the diabetic mouse retina. Ortiz G, Lopez ES, Salica JP, Potilinski C, Fernández Acquier M, Chuluyan E, Gallo JE. Exp Eye Res. 2018 May 18;174:29-39. doi: 10.1016/j.exer.2018.05.013. [Epub ahead of print] PMID: 29778740

Commentary: Fungal lifestyle reflected in serine protease repertoire da Silva RR. Front Microbiol. 2018 Mar 13;9:467. doi: 10.3389/fmicb.2018.00467. eCollection 2018. No abstract available. PMID: 29593699

Loss of HtrA1 serine protease induces synthetic modulation of aortic vascular smooth muscle cells. Ikawati M, Kawaichi M, Oka C. PLoS One. 2018 May 16;13(5):e0196628. doi: 10.1371/journal.pone.0196628. eCollection 2018. PMID: 29768431

Presentation and prognosis of liver disease in alpha-1 antitrypsin deficiency. Townsend S, Newsome P, Turner AM. Expert Rev Gastroenterol Hepatol. 2018 May 28:1-3. doi: 10.1080/17474124.2018.1477589. [Epub ahead of print] No abstract available. PMID: 29768056

Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool. Sun GG, Song YY, Jiang P, Ren HN, Yan SW, Han Y, Liu RD, Zhang X, Wang ZQ, Cui J. PLoS Negl Trop Dis. 2018 May 14;12(5):e0006485. doi: 10.1371/journal.pntd.0006485. eCollection 2018 May. PMID: 29758030

A clip domain serine protease regulates the expression of proPO and hemolymph clotting in mud crab, Scylla paramamosain. Zhang D, Wan W, Kong T, Zhang M, Aweya JJ, Gong Y, Li S. Fish Shellfish Immunol. 2018 May 7;79:52-64. doi: 10.1016/j.fsi.2018.05.013. [Epub ahead of print] PMID: 29747010

Serine Protease Inhibitor Kazal Type I (SPINK1) Mutation: A Risk Factor for Early Onset Chronic Pancreatitis? Hama T, Nakanishi N, Suzuki M, Shima Y, Suzuki H. J Pediatr Gastroenterol Nutr. 2018 May 8. doi: 10.1097/MPG.0000000000002024. [Epub ahead of print] No abstract available. PMID: 29746346

Insight derived from molecular dynamics simulation into dynamics and molecular motions of cuticle-degrading serine protease Ver112. Yang LQ, Chen GY, Li Y, Zhang RP, Liu SQ, Sang P. J Biomol Struct Dyn. 2018 May 28:1-13. doi: 10.1080/07391102.2018.1471418. [Epub ahead of print] PMID: 29718761

Inactivation of the serine protease HTRA1 inhibits tumor growth by deregulating angiogenesis. Klose R, Adam MG, Weis EM, Moll I, Wüstehube-Lausch J, Tetzlaff F, Oka C, Ehrmann M, Fischer A. Oncogene. 2018 May 1. doi: 10.1038/s41388-018-0258-4. [Epub ahead of print] PMID: 29713059

Asymmetric Synthesis of Silanediol Inhibitors for the Serine Protease Coagulation Cascade Enzyme FXIa. Duong HQ, Sieburth SM. J Org Chem. 2018 May 18;83(10):5398-5409. doi: 10.1021/acs.joc.8b00116. Epub 2018 Apr 30. PMID: 29667397

An oxidation-resistant, recombinant alpha-1 antitrypsin produced in Nicotiana benthamiana. Silberstein DZ, Karuppanan K, Aung HH, Chen CH, Cross CE, McDonald KA. Free Radic Biol Med. 2018 May 20;120:303-310. doi: 10.1016/j.freeradbiomed.2018.03.015. Epub 2018 Mar 16. PMID: 29551638

Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity. Laffranchi M, Berardelli R, Ronzoni R, Lomas DA, Fra A. Hum Mol Genet. 2018 May 15;27(10):1785-1793. doi: 10.1093/hmg/ddy090. PMID: 29538751

Jülicher K, Wähner A, Haase K, Barbour KW, Berger FG, Wiehlmann L, Davenport C, Schuster-Gossler K, Stitz J, Cantz T, Eggenschwiler R. Biol Chem. 2018 May 24;399(6):577-582. doi: 10.1515/hsz-2018-0154. PMID: 29498931

The N-terminal-truncated recombinant fibrin(ogen)olytic serine protease improves its functional property, demonstrates in vivo anticoagulant and plasma defibrinogenation activity as well as pre-clinical safety in rodent model. Bora B, Gogoi D, Tripathy D, Kurkalang S, Ramani S, Chatterjee A, Mukherjee AK. Int J Biol Macromol. 2018 May;111:462-474. doi: 10.1016/j.ijbiomac.2017.12.140. Epub 2017 Dec 29. PMID: 29292153

The Role of Computed Tomography for the Evaluation of Lung Disease in Alpha-1 Antitrypsin Deficiency. Campos MA, Diaz AA. Chest. 2018 May;153(5):1240-1248. doi: 10.1016/j.chest.2017.11.017. Epub 2017 Nov 23. Review. PMID: 29175361

Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired Pneumonia. McCarthy C, Dunlea DM, Saldova R, Henry M, Meleady P, McElvaney OJ, Marsh B, Rudd PM, Reeves EP, McElvaney NG. Am J Respir Crit Care Med. 2018 May 15;197(10):1346-1349. doi: 10.1164/rccm.201709-1954LE. No abstract available. PMID: 29144158



This list of publications was generated on PubMed using the following Keywords:plus


    • alpha 1-Antitrypsin
    • alpha one antitrypsin
    • alpha 1 antitrypsine
    • alpha1-AT deficiency
    • alpha-1-AT
    • alpha 1 antiproteinase
    • alpha 1 antiprotease
    • alpha 1 protease
    • alpha 1 proteinase
    • familial emphysema
    • genetic emphysema
    • AATD
    • A1AT
    • hA1AT
    • A1-AT
    • A1P1
    • Prolastin
    • Aralast
    • Zemaira
    • Glassia