Last Month on Pubmed

This is a series of the latest published research on Alpha-1 Antitrypsin Deficiency. It is updated monthly, based on a search. Previous months’ listings are archived in the left sidebar of this page.

May 2017 Publications



Emerging Concepts and Human Trials in Alpha-1-Antitrypsin Deficiency Liver Disease.
Teckman JH. 
Semin Liver Dis. 2017 May; 
PMID: 28564723

Long-term clinical outcomes following treatment with alpha 1-proteinase inhibitor for COPD associated with alpha-1 antitrypsin deficiency: a look at the evidence.

Rahaghi FF, Miravitlles M.
Respir Res. 2017 May 30; PMID: 28558837

Serine protease isoforms in Gloydius intermedius venom: Full sequences, molecular phylogeny and evolutionary implications. 

Yang ZM, Yu H, Liu ZZ, Pei JZ, Yang YE, Yan SX, Zhang C, Zhao WL, Wang ZZ, Wang YM, Tsai IH. 
J Proteomics. 2017 May 26; 
PMID: 28554670

Deterioration of quality of life is associated with the exacerbation frequency in individuals with alpha-1-antitrypsin deficiency - analysis from the German Registry. 

Bernhard N, Lepper PM, Vogelmeier C, Seibert M, Wagenpfeil S, Bals R, Fähndrich S. 
Int J Chron Obstruct Pulmon Dis. 2017 May 12; 
PMID: 28553095

Serine protease inhibitor Kazal type 1(SPINK1) downregulates E-cadherin and induces EMT of hepatoma cells to promote hepatocellular carcinoma metastasis via the MEK/ERK signaling pathway. 

Hai-Yan Y, Chao-Jie G, Yi F, Da-Dao J, Lu LG.
J Dig Dis. 2017 May 23; PMID: 28544403

Complete Draft Genome Sequence of the Actinobacterium <i>Nocardiopsis sinuspersici</i> UTMC102 (DSM 45277<sup>T</sup>), Which Produces Serine Protease. 

Tokovenko B, Rückert C, Kalinowski J, Mohammadipanah F, Wink J, Rosenkränzer B, Myronovskyi M, Luzhetskyy A. Genome Announc. 2017 May 18; PMID: 28522715

A chymotrypsin-like serine protease from Portunus trituberculatus involved in pathogen recognition and AMP synthesis but not required for prophenoloxidase activation. 

Liu H, Liu Y, Song C, Cui Z. 
Fish Shellfish Immunol. 2017 May 15; 
PMID: 28522421

Functional analysis of TcCTLP-5C<sub>2</sub>, a chymotrypsin-like serine protease needed for molting in Tribolium castaneum. 

Albaum D, Broehan G, Muthukrishnan S, Merzendorfer H. 
Insect Biochem Mol Biol. 2017 May 15; 
PMID: 28522347

Tailored Ahp-cyclodepsipeptides as potent non-covalent serine protease inhibitors 

Köcher S, Rey J, Bongard J, Tiaden AN, Meltzer M, Richards P, Ehrmann M, Kaiser M. Angew Chem Int Ed Engl. 2017 May 17; PMID: 28514117

Alpha-1-antitrypsin deficiency-related panniculitis: two cases with diverse clinical courses.
Storan ER, O' Gorman SM, Hawkins P, Aalto L, Murphy A, Markham T.
Clin Exp Dermatol. 2017 May 17; PMID: 28512995  

The pathological Trento variant of alpha-1-antitrypsin (E75V) shows non-classical behaviour during polymerization. 

Miranda E, Ferrarotti I, Berardelli R, Laffranchi M, Cerea M, Gangemi F, Haq I, Ottaviani S, Lomas DA, Irving JA, Fra A. 
FEBS J. 2017 May 15; PMID: 28504839

Treatment of lung disease in alpha-1 antitrypsin deficiency: a systematic review. 

Edgar RG, Patel M, Bayliss S, Crossley D, Sapey E, Turner AM. Int J Chron Obstruct Pulmon Dis. 2017 May 2; PMID: 28496314  

Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome. 

Sarabhai T, Peter C, Bär AK, Windolf J, Relja B, Wesselborg S, Wahlers T, Paunel-Görgülü A. 
PLoS One. 2017 May 11; 
PMID: 28493974

Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression.
Karadagi A, Johansson H, Zemack H, Salipalli S, Mörk LM, Kannisto K, Jorns C, Gramignoli R, Strom S, Stokkeland K, Ericzon BG, Jonigk D, Janciauskiene S, Nowak G, Ellis ECS. 
PLoS One. 2017 May 9; 
PMID: 28486562

Mannan-binding lectin-associated serine protease-1 (MASP-1) mediates immune responses against Aeromonas hydrophila in vitro and in vivo in grass carp.
Dang YF, Shen YB, Xu XY, Wang ST, Meng XZ, Li LS, Zhang M, Hu MY, Lv LQ, Wang RQ, Li JL. 
Fish Shellfish Immunol. 2017 May 4; 
PMID: 28479400

The plant defense and pathogen counterdefense mediated by Hevea brasiliensis serine protease HbSPA and Phytophthora palmivora extracellular protease inhibitor PpEPI10.
Ekchaweng K, Evangelisti E, Schornack S, Tian M, Churngchow N. 
PLoS One. 2017 May 1; PMID: 28459807

Liver Transplantation in Alpha-1 Antitrypsin Deficiency.
Clark VC. 
Clin Liver Dis. 2017 May; PMID: 28364818

Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). 

Naffin-Olivos JL, Daab A, White A, Goldfarb NE, Milne AC, Liu D, Baikovitz J, Dunn BM, Rengarajan J, Petsko GA, Ringe D. 
Biochemistry. 2017 May 2; PMID: 28346784

Human airway trypsin-like protease, a serine protease involved in respiratory diseases.
Menou A, Duitman J, Flajolet P, Sallenave JM, Mailleux AA, Crestani B. 
Am J Physiol Lung Cell Mol Physiol. 2017 May 1; PMID: 28235951

Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, Schwaeble WJ. 
FASEB J. 2017 May; PMID: 28188176

Conformational and functional transitions and in silico analysis of a serine protease from Conidiobolus brefeldianus (MTCC 5185).
Shukla E, Agrawal SB, Gaikwad SM. 
Int J Biol Macromol. 2017 May; 
PMID: 28153464

Solvent effects on ligand binding to a serine protease.
Gopal SM, Klumpers F, Herrmann C, Schäfer LV.
Phys Chem Chem Phys. 2017 May 3; PMID: 28116375

Immune responses in mice vaccinated with a DNA vaccine expressing serine protease-like protein from the new-born larval stage of Trichinella spiralis.
Xu J, Bai X, Wang LB, Shi HN, VAN DER Giessen JWB, Boireau P, Liu MY, Liu XL. 
Parasitology. 2017 May; 
PMID: 28069101

The role of type II transmembrane serine protease-mediated signaling in cancer.
Tanabe LM, List K. 
FEBS J. 2017 May; 
PMID: 27870503




This list of publications was generated on PubMed using the following Keywords:plus


    • alpha 1-Antitrypsin
    • alpha one antitrypsin
    • alpha 1 antitrypsine
    • alpha1-AT deficiency
    • alpha-1-AT
    • alpha 1 antiproteinase
    • alpha 1 antiprotease
    • alpha 1 protease
    • alpha 1 proteinase
    • familial emphysema
    • genetic emphysema
    • AATD
    • A1AT
    • hA1AT
    • A1-AT
    • A1P1
    • Prolastin
    • Aralast
    • Zemaira
    • Glassia​