Last Month on Pubmed

This is a series of the latest published research on Alpha-1 Antitrypsin Deficiency. It is updated monthly, based on a search. Previous months’ listings are archived in the left sidebar of this page.

January 2017 Publications

Conformational and functional transitions and in silico analysis of a serine protease from Conidiobolus brefeldianus (MTCC5185).
Shukla E, Agrawal SB, Gaikwad SM. Int J Biol Macromol. 2017 Jan 30. PMID: 28153464

Interactions between single nucleotide polymorphism of <i>SERPINA1</i> gene and smoking in association with COPD: a case-control study.
Deng X, Yuan CH, Chang. Int J Chron Obstruct Pulmon Dis. 2017 Jan 11;  PMID: 28138235

Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency.
Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM. Proc Natl Acad Sci U S A. 2017 Jan 30.  PMID: 28137880

Insight into the Intermolecular Recognition Mechanism Involved in Complement Component 4 Activation through Serine Protease-Trypsin.
Sinha VK, Sharma OP, Suresh Kumar M. J Biomol Struct Dyn. 2017 Jan 29: PMID: 28132614

Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2.
Shiao F, Liu LO, Huang N, Lai YJ, Barndt RJ, Tseng CC, Wang JK, Jia B, Johnson MD, Lin CY. PLoS One. 2017 Jan 26
PMID: 28125689

Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/alpha-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.
Feng L, Zhang J, Zhu N, Ding Q, Zhang X, Yu J, Qiang W, Zhang Z, Ma Y, Huang D, Shen Y, Fang S, Yu Y, Wang H, Shen Y. Autophagy. 2017 Jan 25: PMID: 28121484

State-of-the-art testing for alpha-1 antitrypsin deficiency.
Kueppers F, Sanders C. Allergy Asthma Proc. 2017 Jan 24.
PMID: 28120746

Solvent effects on ligand binding to a serine protease.
Gopal SM, Klumpers F, Herrmann C, Schäfer LV. Phys Chem Chem Phys. 2017 Jan 24.  PMID: 28116375

Identification of Novel Short C-Terminal Transcripts of Human SERPINA1 Gene.
Matamala N, Aggarwal N, Iadarola P, Fumagalli M, Gomez-Mariano G, Lara B, Martinez MT, Cuesta I, Stolk J, Janciauskiene S, Martinez-Delgado B. PLoS One. 2017 Jan 20; PMID: 28107454

Alpha-1 Antitrypsin Deficiency.
Stoller JK, Lacbawan FL, Aboussouan LS. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Ledbetter N, Mefford HC, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA):University of Washington,
Seattle; 1993-2017. PMID: 20301692

Antibacterial serine protease from Wrightia tinctoria: Purification and characterization
Muthu S, Gopal VB, Soundararajan S, Nattarayan K, S Narayan K, Lakshmikanthan M, Malairaj S, Perumal P. Plant Physiol Biochem. 2017 Jan 3;  PMID: 28088018

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
Kasanmoentalib ES, Valls Seron M, Ferwerda B, Tanck MW, Zwinderman AH, Baas F, van der Ende A, Brouwer MC, van de Beek D. J Neuroinflammation. 2017 Jan 3;  PMID: 28086930

Alpha-1 Antitrypsin Enhances Islet Engraftment by Suppression of Instant Blood-Mediated Inflammatory Reaction.
Wang J, Sun Z, Gou W, Adams DB, Cui W, Morgan KA, Strange C, Wang H. Diabetes. 2017 Jan 9; PMID: 28069642

Immune responses in mice vaccinated with a DNA vaccine expressing serine protease-like protein from the new-born larval stage of Trichinella spiralis.
Xu J, Bai X, Wang LB, Shi HN, VAN DER Giessen JW, Boireau P, Liu MY, Liu XL. Parasitology. 2017 Jan 10; PMID: 28069101

Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?
Wessler S, Schneider G, Backert S. Cell Commun Signal. 2017 Jan 10; PMID: 28069057

Pnserpin: A Novel Serine Protease Inhibitor from Extremophile Pyrobaculum neutrophilum.
Zhang H, Fei R, Xue B, Yu S, Zhang Z, Zhong S, Gao Y, Zhou X.
Int J Mol Sci. 2017 Jan 7; PMID: 28067849

Spirituality, Illness Unpredictability, and Math Anxiety Effects on Negative Affect and Affect-Management Coping for Individuals Diagnosed with Alpha-1 Antitrypsin Deficiency.
Worthington AK, Parrott RL, Smith RA. Health Commun. 2017 Jan 6; PMID: 28059573

The putative serine protease inhibitor (serpin) genes encoded on Echinococcus multilocularis genome and their expressions in metacestodal stage.
Sasaki M, Sako Y. Vet Parasitol. 2017 Jan 15; PMID: 28043383

Discovery Of An Unexplored Protein Structural Scaffold Of Serine Protease From Big Blue Octopus (Octopus Cyanea): A New Prospective Lead Molecule.
Panda S, Kumari L.; Curr Drug Discov Technol. 2017 Jan 2;
PMID: 28042769

Reactive Center Loop Insertion in α-1-Antitrypsin Captured by Accelerated Molecular Dynamics Simulation.
Andersen OJ, Risør MW, Poulsen EC, Nielsen NC, Miao Y, Enghild JJ, Schiøtt B. Biochemistry. 2017 Jan 31;
PMID: 27995800

Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation.
Edgington-Mitchell LE, Barlow N, Aurelio L, Samha A, Szabo M, Graham B, Bunnett N. Bioorg Med Chem Lett. 2017 Jan 15;
PMID: 27923620

Serine protease inhibitor Kazal-type 2 is expressed in the male reproductive tract of carp with a possible role in antimicrobial protection.
Dietrich MA, Słowińska M, Karol H, Adamek M, Steinhagen D, Hejmej A, Bilińska B, Ciereszko A. Fish Shellfish Immunol. 2017 Jan; PMID: 27867114

Spanish Registry of Patients With Alpha-1 Antitrypsin Deficiency: Database Evaluation and Population Analysis.
Lara B, Blanco I, Martínez MT, Rodríguez E, Bustamante A, Casas F, Cadenas S, Hernández JM, Lázaro L, Torres M, Curi S, Esquinas C, Dasí F, Escribano A, Herrero I, Martínez-Delgado B, Michel FJ, Rodríguez-Frías F, Miravitlles M. Arch Bronconeumol. 2017 Jan; PMID: 27323654

Hepatocellular Carcinoma in a Child With Chronic Hepatitis C and α-1 Antitrypsin Heterozygosity.
Viswanathan P, Kogan-Liberman D, Thompson JF, Schwartz D, Pan DH. J Pediatr Gastroenterol Nutr. 2017 Jan; PMID: 25250683



This list of publications was generated on PubMed using the following Keywords:plus


    • alpha 1-Antitrypsin
    • alpha one antitrypsin
    • alpha 1 antitrypsine
    • alpha1-AT deficiency
    • alpha-1-AT
    • alpha 1 antiproteinase
    • alpha 1 antiprotease
    • alpha 1 protease
    • alpha 1 proteinase
    • familial emphysema
    • genetic emphysema
    • AATD
    • A1AT
    • hA1AT
    • A1-AT
    • A1P1
    • Prolastin
    • Aralast
    • Zemaira
    • Glassia​