Finding a cure for Alpha-1 and improving the lives of those affected

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OUR IMPACT

We’ve invested over $100 million into Alpha‑1 research and related programs

From funding breakthrough research to hosting programs and events that keep our community strong and healthy until we find a cure, no other organization does more for families with Alpha‑1.

$100M

in research funded

130

researchers funded

10X

the clinical trials within a decade

TOP STORIES

Alpha-1 Foundation Launches Innovative New Model for Centralized Detection

The Alpha-1 Foundation (A1F) is excited to announce the formation of AlphaDetect, a new non-profit subsidiary of A1F, to lead a […]

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August 20, 2025
July 2025 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the […]

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August 19, 2025
Alpha-1 Foundation Honors Kenneth and Bettina Irvine at Annual Golf Invitational

The Alpha-1 Foundation’s annual Bettina B. Irvine Golf Invitational returned to Greenwich on May 28th, raising critical funds and awareness […]

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July 31, 2025
Alpha, Betsy Scher Shares Sweet Support for Alpha-1

Monday, July 21st, 2025- Betsy Scher and The Highland Park, Illinois community came together in the sweetest way—at Ice Cream […]

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July 29, 2025
The Alpha-1 Community Mourns the Loss of Veteran AlphaNet Coordinator Kathie Sivesind

It is with great sadness that we share the news that AlphaNet Coordinator Kathie Sivesind passed away on July 17, […]

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July 29, 2025
Richie Ramirez’s Alpha Story Featured on CBS Mornings

The Alpha-1 Foundation had the pleasure of meeting Richie Ramirez at the Alpha-1 National Conference, where his passion and story left a […]

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July 22, 2025
Richie’s Ice Cream for Alpha-1 Raises Over $2,100

At just two years old, Richard “Richie” Ramirez was diagnosed with Alpha-1 Antitrypsin Deficiency (Alpha-1), a rare genetic condition that […]

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July 15, 2025
Tell Congress: Support the SOAR Act and Fix Supplemental Oxygen Access

More than 1.5 million Americans rely on supplemental oxygen to breathe. But right now, outdated Medicare rules and poor reimbursement […]

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July 10, 2025
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SPOTLIGHT

A1F Riding for a Reason

Dr. Jennifer Sherman is celebrating her 50th birthday by joining A1F Riding for a Reason for the first time, cruising on her pink tricycle to raise awareness and funds for Alpha-1!

Throughout September, A1F Riding for a Reason is uniting riders, families, and supporters nationwide in honor of Fred C. Walsh’s legacy and A1F’s 30th Anniversary. From local bike paths to signature treks like Escape to the Cape (Sept. 26–28) and Gulf Coast (Oct. 18), participants ride to honor loved ones, advance research, and celebrate three decades of progress.

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