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Augmentation Therapy

Augmentation therapy consists of weekly IV infusions of alpha-1 antitrypsin derived from human plasma. It is used to increase the concentration of the protein in the blood and lungs. Augmentation therapy is the only FDA-approved treatment for alpha-1 antitrypsin deficiency.  Your lung specialist can determine if you are an appropriate candidate for such therapy, which is covered by most insurance plans.

Drug Therapy

This is among the most important types of medical therapy for the newly diagnosed individual with Alpha-1 Antitrypsin Deficiency. Although these are most relevant to lung-affected individuals, remember all Alphas have risks to their lungs. Some of the therapies listed are relevant for all Alpha-1 patients.

Surgical Options

Organ Transplantation of the lung or liver