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This is a series of the latest published research on Alpha-1 Antitrypsin Deficiency. It is updated monthly, based on a search. Previous months’ listings are archived in the left sidebar of this page.

April 2016 Publications

The Diagnostic Value of Alpha-1-Antitrypsin Phenotype in Patients with Granulomatosis with Polyangiitis. Pervakova MY, Emanuel VL, Titova ON, Lapin SV, Mazurov VI, Belyaeva IB, Chudinov AL, Blinova TV, Surkova EA. Int J Rheumatol. 2016 Apr 10. PMID: 27127514

Rare case of eosinophilic granulomatosis with polyangiitis in two patients with α-1-antitrypsin deficiency (PiSZ). Moxey JM, Low EV, Turner AM. BMJ Case Rep. PMID: 27118743

Alpha-1 Antitrypsin Therapy in Cystic Fibrosis and the Lung Disease Associated with Alpha-1 Antitrypsin Deficiency. McElvaney NG. Ann Am Thorac Soc. PMID: 27115956

Alpha-1 Antitrypsin and Lung Cell Apoptosis.  Serban KA, Petrache I. Ann Am Thorac Soc. PMID: 27115949

Neutrophil Fates in Bronchiectasis and Alpha-1 Antitrypsin Deficiency. Russell DW, Gaggar A, Solomon GM. Ann Am Thorac Soc. PMID: 27115946

Pulmonary Physiology of Chronic Obstructive Pulmonary Disease, Cystic Fibrosis, and Alpha-1 Antitrypsin Deficiency. Stockley JA, Stockley RA. Ann Am Thorac Soc. PMID: 27115945

Chairman's Summary: Can Cystic Fibrosis and Alpha-1 Antitrypsin Deficiency Inform Chronic Obstructive Pulmonary Disease? Wanner A. Ann Am Thorac Soc. PMID: 27115943

Panniculitis associated with alpha-1 antitrypsin deficiency: from early descriptions to current targeted therapy.  Cardoso JC. Br J Dermatol. PMID: 27115579

Autophagy Induced by Exogenous Bile Acids is Therapeutic in a Model of Alpha-1-AT Deficiency Liver Disease. Tang Y, Fickert P, Trauner M, Marcus NY, Blomenkamp KS, Teckman J. Am J Physiol Gastrointest Liver Physiol. 2016 Apr 21. PMID: 27102560

Altered glycosylation, expression of serum haptoglobin and alpha-1-antitrypsin in chronic hepatitis C, hepatitis C induced liver cirrhosis and hepatocellular carcinoma patients.  Mondal G, Saroha A, Bose PP, Chatterjee BP. Glycoconj J. 2016 Mar 31. PMID: 27034286

Additional N-glycosylation in the N-terminal region of recombinant human alpha-1 antitrypsin enhances the circulatory half-life in Sprague-Dawley rats. Chung HS, Kim JS, Lee SM, Park SJ. Glycoconj J. 2016 Mar 7. PMID: 26947874 

A study of common Mendelian disease carriers across ageing British cohorts: meta-analyses reveal heterozygosity for alpha 1-antitrypsin deficiency increases respiratory capacity and height. North TL, Ben-Shlomo Y, Cooper C, Deary IJ, Gallacher J, Kivimaki M, Kumari M, Martin RM, Pattie A, Sayer AA, Starr JM, Wong A, Kuh D, Rodriguez S, Day IN.  J Med Genet. 2016 Feb 1. PMID: 26831755

Neutrophilic panniculitis associated with alpha-1-antitrypsin deficiency: an update. Blanco I, Lipsker D, Lara B, Janciauskiene S. Br J Dermatol. 2016 Jan 27. PMID: 26595240

Lung Transplantation in Alpha-1-Antitrypsin Deficiency. Stone HM, Edgar RG, Thompson RD, Stockley RA. COPD. 2015 Oct 21. PMID: 26488418

[Profiles of cases included in the Spanish registry of patients with alpha-1 antitrypsin deficiency]. Lara Gallego B, Castillo Carullón S, Martínez Martínez MT, García Reymundo M, Miravitlles M. An Pediatr (Barc). 2015 Jul 23.Spanish. PMID: 26212422





This list of publications was generated on PubMed using the following Keywords:plus

    • alpha 1-Antitrypsin
    • alpha one antitrypsin
    • alpha 1 antitrypsine
    • alpha1-AT deficiency
    • alpha-1-AT
    • alpha 1 antiproteinase
    • alpha 1 antiprotease
    • alpha 1 protease
    • alpha 1 proteinase
    • familial emphysema
    • genetic emphysema
    • AATD
    • A1AT
    • hA1AT
    • A1-AT
    • A1P1
    • Prolastin
    • Aralast
    • Zemaira
    • Glassia​